The drivers of both trucks suffered only minor injuries in the crash. NSW Police said the two men, aged 26 and 49, were taken to Bankstown Hospital for mandatory testing.
NSW Ambulance Inspector Karen Nichols said paramedics arrived to “an absolutely horrendous scene”.
Paramedics “worked with other emergency services in an extremely complex situation to get to patient as quickly as possible”, she said.
Henry Lawson Drive has been closed in both directions from the M5 to Milperra Road, and diversions are in place.